The Kidney–Heart Connection
Disease burden
Chronic kidney disease in patients with type 2 diabetes increases the risk of cardiovascular disease, infection, cancer and death
Diabetes exerts a high global disease burden and increases the risk of various comorbidities. Among the multiple comorbidities affecting people with type 2 diabetes, chronic kidney disease is one of the most common complications, occurring in over 40% of cases.2 Chronic kidney disease has dramatic consequences, increasing the risk of end-stage kidney disease requiring dialysis or transplantation, as well as cardiovascular disease, infection, cancer and death.
The global disease burden of type 2 diabetes and chronic kidney disease.
CKD, chronic kidney disease; T2D, type 2 diabetes
1. International Diabetes Federation 2019. IDF Diabetes Atlas, 9th edn. [accessed 12 August 2020]
2. Wu B, et al. BMJ Open Diab Res Care 2016;4:e000154
Type 2 diabetes causes damage to various organs, leading to complications and comorbidities such as chronic kidney disease.
CKD, chronic kidney disease; T2D, type 2 diabetes
1. International Diabetes Federation 2019. IDF Diabetes Atlas, 9th edn. https://diabetesatlas.org/en/ [accessed 18 May 2020]
2. National Kidney Foundation. Am J Kidney Dis 2007;49(suppl 2):S1–S180
Having chronic kidney disease and diabetes shortens life expectancy*1-4
*At age 30, compared with patients without diabetes or chronic kidney disease. The study population consisted of 543,412 adults who participated in a self-paying comprehensive health surveillance programme between 1994 and 2008.
CKD, chronic kidney disease; CV, cardiovascular; T2D, type 2 diabetes
1. Afkarian M, et al. J Am Soc Nephrol 2013;24:302–308
2. Wen CP, et al. Kidney Int 2017;92:388–396
3. Levin A, et al. Kidney Int Suppl 2013;3:1–150
4. Fox CS, et al. Lancet 2012;380:1662–1673
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